AMT shall include the data from the new trial in the Marketing Authorization Software for Glybera. The submission of the dossier to the European Medications Agency is planned for the next half of 2009. LPLD can be an orphan disease, today that no treatment exists. The disease is due to mutations in the LPL gene, resulting in highly reduced or absent activity of LPL protein in patients. This protein is needed in order to break down large fat-carrying contaminants that circulate in the blood after every meal. When such particles, known as chylomicrons, accumulate in the bloodstream, they might obstruct small blood vessels. This outcomes in recurrent and serious acute inflammation of the pancreas, known as pancreatitis, the most debilitating complication of LPLD.One is the fasting plasma glucose check and the various other may be the glucose tolerance check . If you are found to be pre-diabetic, after that there are always a couple of actions you can take to lower your risks. First of all, if you are overweight, lose it then. Secondly, if you are inactive physically, then start moving. Quit being a inactive and get up and begin your body moving. Run or walk, but quit your sitting! Start a low fat, low calorie diet and an application of exercises. It has been established that both together will keep you from falling headlong right into type 2 diabetes.